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November 1960

Radioisotope Studies of Fatty Acid Metabolism

Arch Dermatol. 1960;82(5):849-850. doi:10.1001/archderm.1960.01580050191037

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This book, which is one of the series of monographs on nuclear energy, is written primarily for the student of biochemistry, but the advances in the concepts of fatty acid metabolism as revealed by radioisotope studies in the last decade will be of interest to all physicians. This volume, however, is not for those who are unfamiliar with the biochemistry of lipids or for those unwilling to struggle once more with the language of biochemistry.

Chapter 1 on digestion and absorption summarizes the radioisotope studies which led to the conclusion that the long-chain fatty acids appear in the lymph largely as triglycerides regardless of the form of fatty acid feeding. The digestion of triglycerides to monoglycerides by the action of lipase is also discussed here. In Chapter 2—transport, deposition, and mobilization of fatty acids—the authors review the evidence relating to the liver as a modifier of fatty acids and the

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