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December 1960


Arch Dermatol. 1960;82(6):1017-1024. doi:10.1001/archderm.1960.01580060173039

Preliminary Report: Drug Eruptions Based on Photomechanism. Presented by Dr. Leonard C. Harber (by invitation). 

Discussion  Dr. Frances Pascher: I want to congratulate and thank Dr. Harber for his beautifully developed presentation. I saw a number of cases of purpura last spring and early summer attributable to Diuril and Hydrodiuril in addition to those cited this evening. Each of my cases was an example of nonthromobocytopenic purpura. One case of thrombocytopenic purpura has been reported (Gesink, M. H., and Bradford, H. A.: J.A.M.A. 172:556-559 [Feb. 6] 1960). However, the capillary system rather than the hemopoetic system is the target organ in most instances.The lichen-planus-like reactions are most interesting. Some years ago Dostrovsky and Sagher (Arch. Dermat. & Syph. 59:308-328 [March] 1949) described a group of cases of lichen planus with an inverse distribution from subtropical countries. Their cases had one feature in common with the cases described this evening,

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