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February 1961

Pathologic Dynamics of Human Hair Loss: I. Telogen Effluvium

Author Affiliations


From the Department of Dermatology of the University of Pennsylvania Medical School, and the Hospital of the University of Pennsylvania, Philadelphia.

Arch Dermatol. 1961;83(2):175-198. doi:10.1001/archderm.1961.01580080005001

This study concerns the behavior of the human follicle under stresses which cause temporary loss of hair. Many different agencies cause hair shedding.1 For some years now, I have been watching what happens to the follicle in a variety of natural and experimental alopecic conditions. Out of these observations has grown a biological generalization, the presentation of which is the main business of this essay.

To grasp the meaning of this generalization, requires a thorough understanding of the hair cycle, and, in particular, catagen, that brief epoch during which a growing follicle (anagen) becomes transformed into a resting one (telogen). The prelude to the present theme is to be found in a previous paper dealing with the dynamics of human catagen.2 Further important readings are Montagna's3 analyses of hair cycle mechanics, and a recent study of catagen by Ellis and Moretti.4 The dynamics of change in

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