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February 1961


Arch Dermatol. 1961;83(2):343-347. doi:10.1001/archderm.1961.01580080173026

Allergic Vasculitis. Douglas Torre, M.D. 

Sites.—  Lower extremities and buttocks.

Duration.—  Four years.

History.—  A 20-year-old white student reported that since age 16, erythematous macular lesions, accompanied by a tingling sensation, would appear on both feet within a half hour of exercise, such as bowling or dancing. Approximately 2 hours later fever was experienced. After 2 or 3 days the erythematous lesions became brownish. Residual, small, punctate areas of pigmentation remained. The eruption has gradually extended to cover the legs, thighs, and buttocks. In the past 2 weeks, lesions have appeared on the hands.

Laboratory.—  CBC, platelet count, bleeding and clotting time, and capillary fragility test within normal limits.

Discussion  Dr. Nelson: I think that this young lady, who has had recurrent purpura on the legs after exercise for the past 4 years, may well have a dysproteinemia of some sort. I would look for both cold-precipitable globulins and hypergammaglobulinemia.

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