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March 1961

Darier's Disease: Report of a Case Complicated by Kaposi's Varicelliform Eruption

Author Affiliations


From the Department of Dermatology, Henry Ford Hospital (Clarence S. Livingood, M.D., Director).

Arch Dermatol. 1961;83(3):425-429. doi:10.1001/archderm.1961.01580090075009

Kaposi's varicelliform eruption is an unusual, though by no means rare, complication of a preexisting dermatosis, usually atopic eczema. In Kaposi's classic description,1 the eruption consists of grouped vesicles the size of a lentil, filled with clear serum. The majority of the lesions are umbilicated and look like varicella vesicles. The involved skin is turgid and edematous. The vesicles develop acutely, and often appear in successive crops for as long as a week. As the eruption fades, the earliest lesions rupture, become encrusted, and fall off, exposing the corium. The majority of the vesicles will appear on skin already involved by eczema. A few vesicles appear on previously intact skin in the neighborhood. There may be fever and severe constitutional symptoms.

The clinical picture is so characteristic that it offers little difficulty in diagnosis. However, it was not until 1941 that Seidenberg proposed that the syndrome was a disseminated