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March 1961

A Clinical Study of Malignant Melanoma

Author Affiliations


From Department of Medicine, Division of Dermatology, Vanderbilt University School of Medicine.

Clinical Professor of Dermatology, Vanderbilt University School of Medicine, Nashville, Tenn. (Dr. Buchanan).

Arch Dermatol. 1961;83(3):447-458. doi:10.1001/archderm.1961.01580090097013

Malignant melanoma remains a very challenging and unpredictable problem even though it has been the subject of many studies over the years. Efforts to predict its behavior based on sex and age of the patient, site of the primary tumor, microscopic appearance of the malignancy, duration of the pigmented lesion, and history of trauma have been disappointing. The fact that the problem is still encountered and patients must suffer and die, because of the inherent nature of the illness, the unpardonable delay in diagnosis, and the inadequate treatment, warrants reexamination of the subject.

The lack of agreement regarding the extent of radical treatment, whether node dissection should be done routinely or whether local excision, node dissection, and removal of the lymphatics in continuity should be followed when the site of the tumor allows this approach to be practical, justifies presentation of a small series in which the treatment method has

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