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April 1961

Clinical Manifestations of Mouse Favus in Man

Author Affiliations


Department of Bacteriology and Immunology, McGill University (Dr. Blank); Hôpital Notre Dame (Dr. Leclerc); Department of Medicine, Subdepartment of Dermatology, Royal Victoria Hospital (Dr. Telner).

Arch Dermatol. 1961;83(4):587-597. doi:10.1001/archderm.1961.01580100051007

Introduction  The causative organism of mouse favus, Microsporum quinckeanum (Quincke's α-Pilz, Achorion quinckeanum), has attracted wide interest since Quincke's publications20-22 on this particular type of dermatomycosis. Although Bodin5 and Bloch4 confirmed Quincke's findings, the dermatophyte, a distinct species, and the manifold clinical manifestations caused by it were not well understood for a long time. There are several reasons for this misapprehension: 1. Favus of mice due to Microsporum quinckeanum is less frequent than human favus due to Trichophyton schönleini. In Europe, where human favus is endemic, Quincke's publications induced several authors7-9,15,18 to search for this dermatophyte. They isolated nothing but T. schönleini from favic lesions. 2. A fungus other than T. schönleini causing the formation of scutula did not fit into the doctrinaire schemes of the dermatologists of the last century. They refused to believe that the clinical entity favus, i.e., the presence of scutula, was