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April 1961


Arch Dermatol. 1961;83(4):705-707. doi:10.1001/archderm.1961.01580100169033

Bullous Lichen Sclerosus et Atrophicus. Presented by Dr. Fred F. Feldman and (by invitation) Dr. Alfred G. Lerner.  A biopsy specimen was taken from the bullous area of the right breast on Feb. 25, 1960. Histologic examination reveals a mild, hyperkeratotic, squamous epithelium lifted by subepidermal bullous edema, beneath which is a dense hyalinized sclerosis. Minimal infiltrate is present. The slide was diagnosed as lichen sclerosus et atrophicus.

Discussion  Anita Gelber, M.D.: This woman has bullous lichen sclerosus et atrophicus. The age of onset varies from early childhood to old age. A greater number of cases occur past middle age. This patient presents what is considered to be characteristic objective symptoms. The various sized, white (mother-of-pearl) patches consist of round and oval, well-defined, discrete papules on shoulders, neck, trunk, and genitalia. Under the right breast is a red, denuded, weeping hemorrhagic area. Under the left breast and vulva is white,

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