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Article
May 1961

ECZEMA VACCINATUM

Arch Dermatol. 1961;83(5):758. doi:10.1001/archderm.1961.01580110046005

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Abstract

To the Editor:—  This correspondence concerns the article on page 225/171 of the January, 1961, issue of the Archives of Dermatology, entitled Eczema Vaccinatum.Dr. Sidney Barsky said: "Within 24 hours of hospitalization, the lesions became generalized with sparing of the palms and soles."Dr. Charles D. Bell, Lincoln, Neb.: "I would like to know why the palms and soles were spared in this patient."Dr. Sidney Barsky: "I cannot answer why this patient did not have lesions on the palms and soles."The answer is simple. The patient was not inoculated with smallpox virus but by its first cousin, cowpox virus. When man contracts cowpox from that animal, the infection produces characteristic nodules on his hands, but he does not have a generalized eruption unless he is an atopic individual. Otherwise he has no generalized eruption, and even in patients who have developed eczema vaccinatum, they do not

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