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May 1961

A Disposable Syringe for Intralesional Injections

Arch Dermatol. 1961;83(5):848-849. doi:10.1001/archderm.1961.01580110136022

Increasing use has been made of intralesional injections for the treatment of a number of chronic dermatologic disorders. The dermatoses reported to respond to the local injection of steroids include alopecia areata, alopecia totalis, alopecia universalis, circumscribed neurodermatitis, psoriasis, atopic dermatitis, lichen planus, keloid, nummular eczema, granuloma annulare, erythema annulare centrifugum, dermatitis herpetiformis, pemphigus, and discoid lupus erythematosus.1-5

In addition to the intralesional injection of lesions such as those listed above, the dermatologist makes use of intracutaneous or subcutaneous injections routinely for the administration of many drugs, infiltration of lesions with local anesthetics prior to biopsy or excision, intradermal testing in allergic conditions, etc. This extensive employment of injections creates several important health problems, as well as many minor ones.

Requirements for syringes used may be listed as follows: (1) sterility (especially concerning serum hepatitis),6,7 (2) freedom from contamination,8,9,11 (3) freedom from leakage and contact with surroundings,