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May 1961


Arch Dermatol. 1961;83(5):855-862. doi:10.1001/archderm.1961.01580110143026

Toxic Vesicular Eruption. Presented by Harry Levitt, M.D.  A 29-year-old man has had a moderately pruritic, vesicular eruption of the face and scalp for the past 6 months. It responded well to boric acid compresses and Vioform hydrocortisone cream, but did not clear completely; a severe flare occurred in the past month.He denies the ingestion of any medication except prednisone, which was prescribed one month ago.His general health is good, and there is no history of eczema, hay fever, asthma, or any other allergic reaction.

Physical Examination.—  The patient is a well developed and nourished man. There are superficial 0.5 cm. to 1 cm. flaccid, discrete bullae and superficial crusts of the face and scalp. Some of the areas of the face have healed with atrophic scars.A specimen was taken for biopsy on July 19, 1960, and is presented.

Discussion  Samuel Ayres, III, M.D.: I thought that

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