Erythroplasiform lesions, particularly on mucous membranes, always present a complicated differential diagnostic problem. However, out of all the data on erythroplasia and interpretations of that data that have accumulated since the time (1911) of Queyrat,1 certain meaningful concepts about such processes have crystallized. By now conditions that look clinically like erythroplasia of Queyrat may be cast into 3 categories as follows.
The Erythroplasia to Which the Eponym, Queyrat, May Properly Be Added.— This is an obligatory precancerosis (or an actual cancer in situ) that is a variant by Bowen's disease. Whatever clinical differences it shows from Bowen's disease in extragenital sites are accounted for by its location on mucous or mucocutaneous membranes. The histologic picture is distinctly malignant, and although the process may remain confined intraepidermally for a long time, it will terminate as frank prickle cell epithelioma with capacity to metastasize if left to itself untreated.
HYMAN AB, LEIDER M. Erythroplasia of the Female Genitalia: Report of Two Cases of a Benign Form (Plasmacytosis Pudendi). Arch Dermatol. 1961;84(3):381–385. doi:10.1001/archderm.1961.01580150027004
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