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September 1961

Study of the Galvanic Skin Response in Atopic Dermatitis

Author Affiliations


Division of Dermatology, Department of Medicine, University of California at Los Angeles, and Medical Service, Veterans Administration Center, General Medical and Surgical Service Hospital (Dr. Perry, Dr. Wright, and Dr. Maliner); Departments of Psychology and Engineering, University of California at Los Angeles (Dr. Mount).

Arch Dermatol. 1961;84(3):496-502. doi:10.1001/archderm.1961.01580150142025

Introduction  In recent years Perry, Mount, and coworkers have reported their findings in experiments with the Galvanic Skin Response (GSR).1-4 They have demonstrated the effects of drugs and controls in standardization experiments, and the results have consistently shown a rise in GSR level after sweat-stimulating drugs and a fall after sweat-inhibiting compounds. The present study was undertaken to evaluate the effect of the same drugs on the GSR in atopicdermatitis and compare their reactions with controls.

Materials and Methods  The test group included 20 subjects (10 normal and 10 with atopic dermatitis). The normal individuals were college students ranging in age from 18-28. The atopics varied in age from 25-55, and all were hospitalized in a Veterans hospital for treatment of their skin disease. Their selection was based on the following criteria as outlined by Pillsbury, Shelley, and Kligman.5 All subjects had dermatitis intermittently and for varying periods

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