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September 1961

Familial Incidence of Pemphigus

Author Affiliations


Department of Dermatology, Virginia Mason Hospital and Clinic.

Arch Dermatol. 1961;84(3):506-508. doi:10.1001/archderm.1961.01580150152029

The familial incidence of pemphigus has been mentioned on a few occasions in the medical literature, generally as a minor note in journals or as a footnote in textbooks. Morris,1 in his textbook, mentions the fact that Kaposi attended a patient in whom 3 other members of the family died of pemphigus (details are not recorded), and he stated that he himself had treated 3 members of one family with the disease. Granirer2 reported the death of a 64-year-old Jewish woman in 1948, two of her brothers having died of pemphigus in 1925 and 1932. This was apparently reported again by Miller and Frank,3 as the details and events of their report closely parallel that of Granirer. Feldman4 makes reference to 2 brothers dying 10 years apart of pemphigus, and Greenbaum5 reports 2 instances of pemphigus in relatives: father and son on the one hand