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November 1961

Fungistatic and Fungicidal Tests with Ethyl Alcohol

Author Affiliations


From the Department of Dermatology, University of Miami School of Medicine, Miami, Fla.

Grantee of Instituto de Alta Culture (Portuguese Ministry of Education) and Luso-American Educational Commission (U.S. Government). Present address: Lab. Micologia, Clinica Dermatologica, Universitaria de Lisboa, Hospital de Santa Maria, Lisboa 4, Portugal.

Arch Dermatol. 1961;84(5):790-791. doi:10.1001/archderm.1961.01580170084010

In a previous unreported experiment* the antifungal effect of 10% Lysol (disinfectant with orthophenylphenol as principal germicidal ingredient) was compared with several dilutions of two different soaps, the common domestic "Offenbach" and the antiseptic "Nobater" (Laboratories Chantereau, Arcueil, Seine). Using a technique described by Frey et al.,1 Lysol showed fungicidal effect in vitro against Trichophyton violaceum, T. tonsurans, T. mentagrophytes, T. schoenleinii, T. megninii, and Microsporum canis. Dilutions of both soaps at 1/1,000, 1/100, and 1/10 did not inhibit growth of the same dermatophytes.

As pointed out recently2 there are very few references reporting the effect of ethyl alcohol on the normal growth of dermatophytes. In 1933, Emmons3 reported that T. gypseum was not inhibited after 30 minutes' immersion in 50% alcohol but did not develop after 30 minutes in 85% alcohol. Loewenthal4 has just studied the effect of 70% ethyl alcohol on hairs infected by