Eccrine spiradenoma is a benign, painful tumor of the skin, which probably originates in the coil of the (eccrine) sweat glands and presents a characteristic clinical and pathological picture.
The classical description of the eccrine spiradenoma by Kersting and Helwig1 in 1956 defined this condition as a distinct clinicopathological entity. Since then this disease has been transferred from the realm of the pathologist alone, and increased awareness of this condition has led to diagnosis or at least suspicion on clinical grounds.
Most eccrine spiradenomata are solitary tumors and therefore removal of the tumor for histological study usually prevents further clinical evaluation.
Stegmaier and Kersting2 observed a case of multiple eccrine spiradenoma tumors clinically and reported their preliminary pharmacologic studies, the most interesting of these being intermittent attacks of pain after injection of oxytocin (Pitocin) into the lesions.
A case of multiple eccrine spiradenoma in a young man presented
ZIPRKOWSKI L, KRAKOWSKI A. Contribution to Eccrine Spiradenoma. Arch Dermatol. 1961;84(5):792–797. doi:10.1001/archderm.1961.01580170086011