Recent reports of colloid degeneration of the skin indicate that the disease is not rare.1 The usual type of cutaneous colloid degeneration known as colloid milium, or pseudomilium, is manifested by small nodules or pellucid papules of the face, neck, and hands, which microscopically exhibit circumscribed, small foci of altered connective tissue in the dermal papillae. There is another type of cutaneous colloid degeneration which was reported by Labadie2 in 1925 and by Reuter and Becker3 in 1942. It does not fit the pattern established by Wagner's classical description,4 but consists of plaques in which there is diffuse degenerative change throughout the cutis. This type is rare and may be confused with amyloidosis. The following case is an illustrative example.
The patient is a 43-year-old white male who was born in Ragland, Ala. At age 5 years he moved to Florida, where he has lived continuously
SULLIVAN M, ELLIS FA. Facial Colloid Degeneration in Plaques. Arch Dermatol. 1961;84(5):816–823. doi:10.1001/archderm.1961.01580170110015
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