The etiologic role of iodine as encountered in the diets of patients with adolescent acne vulgaris has long been of concern to physicians. Apparently because it has been unequivocably shown that iodine given as a medicine can cause an acneiform eruption, diets restricting foods and condiments with high iodine content have been prescribed for these patients with varying degrees of vigor by many physicians, including dermatologists. For example, the authors of several American dermatologic texts recommend restriction of iodized salt and/or "seafoods." Objective evidence supporting any attitude on dietary iodine for these patients is indeed sparse. The most extreme view encountered is that of Barefoot1 who felt that a group of patients with acne vulgaris on a low iodine diet were further benefited by the administration of nicotinic acid, which was supposed to "neutralize or counteract the aggravating factors of iodides."Owing to the paucity of solid evidence
HITCH JM, GREENBURG BG. Adolescent Acne and Dietary Iodine. Arch Dermatol. 1961;84(6):898–911. doi:10.1001/archderm.1961.01580180014002
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