Over a period of several years, I have been troubled by the seemingly irrational feeling that an unusual percentage of my patients with atopic dermatitis had brown eyes. During 2 intervals in the past 10 years, records of eye color in consecutive patients with atopic dermatitis have been kept. These records bear out this impression, almost two-thirds of these persons having brown eyes. A guess by a colleague in ophthalmology that the general population of Iowa averages only 40% brown eyes has likewise been proved true in 2 samples of persons used as controls, and the same 40% proportion of brown-eyed individuals occurred in a continuous sampling of patients with skin disease.
The study was begun in 1951 and continued for 2 years. At that time a departmental move interrupted the study, and it was temporarily put aside, then resurrected in 1957, and continued to the present time. Because
CARNEY RG. Eye Color in Atopic Dermatitis. Arch Dermatol. 1962;85(1):17–21. doi:10.1001/archderm.1962.01590010023003
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