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January 1962

Two Cases of Unusual Vacuolar Degeneration of the Epidermis: Epidermodysplasia Verruciformis?

Author Affiliations


Department of Dermatology and Syphilology, University of Wisconsin Medical School, (Dr. Johnson); Emeritus Member, Section of Dermatology, Mayo Clinic and Mayo Foundation (Dr. Montgomery); Duluth Clinic, formerly Resident at University of Wisconsin Medical School (Dr. Tuura); Section of Dermatology, Mayo Clinic and Mayo Foundation (Dr. Winkelmann).

Arch Dermatol. 1962;85(1):53-64. doi:10.1001/archderm.1962.01590010059008

In 1955 when 2 of us (S.J. and J.T.) saw a patient with cutaneous eruption which clinically suggested verruca plana but which had a pathologic picture that had not been seen previously by several dermatopathologists to whom sections were sent, we did not think too much of it until one of us (H. M.), who was one of the dermatopathologists who had studied the histopathologic sections from our case, found another person with the same pathologic picture.

Report of Cases 

Case 1.—  This 27-year-old male student from Bagdad, Iraq, was seen by us (S.J. and J.T.) in February, 1955, at the University of Wisconsin Hospitals and Clinics for a skin condition which had been present for at least 17 years. The patient described the early lesions as being oval, slightly pigmented, and localized to the dorsum of the hands. Throughout pubescence new lesions appeared on the neck, face, arms, and