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May 1962


Arch Dermatol. 1962;85(5):651-654. doi:10.1001/archderm.1962.01590050081021

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Pseudoxanthoma Elasticum with Gastric Melena. Presented by Dr. Leonard Katz and Dr. George Curtis by courtesy of Dr. Charles H. Brown of the Department of Gastroenterology of the Cleveland Clinic. 

History.—  A 22-year-old white housewife has had unusual progressive skin changes since early childhood. They began on the neck and gradually involved all the flexural areas in the body. At age 15 she had an episode of melena and anemia. In the past year the patient has been bruising with slight trauma.On May 22, 1961, she developed massive hematemesis necessitating exploratory laparotomy at another hospital. At operation the stomach was opened widely, and the bleeding was seen to be coming from numerous small longitudinal lacerations in the cardia. The lacerations were oversewn, and the bleeding stopped. Postoperatively, the patient developed daily melena and severe anemia. She was transferred to the Cleveland Clinic Hospital on June 8, 1961, where she

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