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May 1962


Arch Dermatol. 1962;85(5):662-667. doi:10.1001/archderm.1962.01590050092024

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Epidermolysis Bullosa with Pachyonychia in Three Generations. Presented by Dr. Stanton B. May.  Patients are presented from the Skin Clinic of the Glendale Sanitarium-Hospital. The mother, aged 25, a white female, states that all her life she has had deformed finger- and toenails and that on her feet she gets blisters which form heavy callosities. During childhood the condition was particularly aggravated by warm weather and anything causing sustained friction on her feet and hands. In the past a few lesions had appeared on her palms but none appeared there during the last few years. X-ray treatments in 1955 allegedly made the eruption worse. This patient's mother also has had deformed nails and a blistering tendency of the fingers and feet. The VDRL was negative.The 5-month-old son of the above patient has had deformed finger- and toenails since birth. His nails are discolored yellow, and the distal ends are

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