Passive cutaneous anaphylaxis has been demonstrated to be an extremely sensitive method for the demonstration of antigen-antibody reactions of the immediate type.1-3 The most commonly used form of this testing procedure is based on the localization of a dye at the site of an intradermal injection of antibody. Antigen necessary to elicit the reaction is administered intravenously along with Evans blue solution several hours after the intradermal injection of antibody. Visible skin reactions appear within minutes at the sites of antigen-antibody combination. These reactions can generally be more accurately assessed by measurements on the internal skin surface.Recently, a modification of this procedure has been reported capable of producing reactions when psoriatic serum was injected intradermally and after a latent period psoriatic skin homogenates were injected with dye intravenously, suggesting an immune mechanism to be operative in psoriasis.4The study to be reported here was undertaken in
HARBER LC, MARCH C, OVARY Z. Lack of Passive Cutaneous Anaphylaxis in Psoriasis. Arch Dermatol. 1962;85(6):716–719. doi:10.1001/archderm.1962.01590060026004
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