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June 1962


Arch Dermatol. 1962;85(6):753-758. doi:10.1001/archderm.1962.01590060063017

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Malignant Acanthosis Nigricans, Malignant Papilloma of the Bladder (Grade 1), Leiomyoma(?) of the Stomach, Transitional Cell Carcinoma of Left Kidney, Latent Syphilis. Presented by Dr. Helen O. Curth.  About 1 year ago an 81-year-old Negro man noticed changes in the color of his skin and gross hematuria. In the past 6 months he has been hospitalized on 2 occasions in the Presbyterian Hospital for investigation of acanthosis nigricans and treatment of whatever pathology of other organs might be found. Five months ago a papillary tumor of the bladder was resected and its base fulgurated. One month later exploratory laparotomy was undertaken because x-ray examination of the kidneys showed failure to visualize the upper pole of the left kidney, and x-ray and gastroscopic examination of the stomach showed abnormality in HCl excretion and altered function of the pyloric antrum. At operation it was found necessary to remove the left kidney and

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