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July 1962

Recurrent Keratoacanthoma of the Lip

Author Affiliations


New York University Schools of Medicine and the Skin and Cancer Unit of University Hospital.

Resident, Department of Dermatology (Dr. Silberberg); Associate Professor, Department of Dermatology (Dr. Kopf); Professor and Chairman, Department of Dermatology (Dr. Baer).

Arch Dermatol. 1962;86(1):44-53. doi:10.1001/archderm.1962.01590070050007

Although the existence of recurrent keratoacanthoma of the lip has been recognized for some time, its relatively rare occurrence and the importance of its differentiation from squamous cell carcinoma, which it can closely simulate, prompt us to report our observations of a pertinent case. Burman et al.10 in 1956 described a recurrent keratoacanthoma of the lip in a 68-year-old white male who developed within a 10-week period an irregular, soft, crusted excrescence occupying almost one-half of the lower lip. A clinical diagnosis of molluscum pseudocarcinomatosum (keratoacanthoma) was made because of the rapid growth in a short time, as well as the gross characteristics. Biopsy of the lesions revealed a "low grade epidermoid carcinoma." The lesion was treated by shaving off only the polypoid portion flush with the adjacent normal lip surface. Five weeks after surgery the lip appeared healed. However, 3 months after treatment, a mass similar to but