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July 1962


Arch Dermatol. 1962;86(1):117-123. doi:10.1001/archderm.1962.01590070123033

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Diagnosis: Bowen's Disease. Presented by Dr. Adrian Brodey. 

Description:  The patient, a white male, age 40, in good health, consulted me on Dec. 13, 1961, for the treatment of a lesion of the right fifth finger of 1 year's duration. The lesion had begun as a small papule and gradually increased to its present size. There was no history of arsenic ingestion. The lesion was asymptomatic except for pruritus.Physical examination revealed a slightly elevated, erythematous, round, plaquelike lesion, well marginated and with superficial scaling, located on the dorsal aspect of the distal phalanx of the right fifth finger. The lesion was 1.0 cm. in diameter. Biopsy examination was performed and confirmed the clinical impression of a neoplastic lesion. Microscopic diagnosis by Dr. Sachs was Bowen's disease. The microscopic description was as follows: "The epidermis is decidely thickened, the surface is covered by an increased, dense, horny layer. Within the

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