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August 1962

Cicatricial Pemphigoid and Skin Grafts

Author Affiliations


Rupert Hallam Department of Dermatology, Royal Infirmary.

Arch Dermatol. 1962;86(2):226-228. doi:10.1001/archderm.1962.01590080096013

Lever (1951, 1953) first clearly differentiated ocular pemphigus, which he renamed benign mucous membrane pemphigoid and, more recently, cicatricial pemphigoid, from pemphigus vulgaris. He pointed out the benign course, the subepidermal position of the bullae, and, most important of all, the tendency for the bullae to form scars on mucosae and skin. Church and I (1953) drew attention to the lesions on mucous membranes other than the conjunctiva and confirmed (1956) Lever's observations that there were 2 types of skin lesions. The most common is a generalized bullous eruption of short duration which is similar to the bullous eruption of pemphigoid. The second is a localized erythematous plaque, the site of recurring bullae, which may become scarred or ulcerated. Such ulceration is superficial, moist, and with little evidence of epithelialization. The localized skin lesions occur near affected mucous surfaces and are not unusual on the scalp. Lortat-Jacob (1958) stressed that