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September 1962


Author Affiliations

57 West 57th St. New York 19

Arch Dermatol. 1962;86(3):267. doi:10.1001/archderm.1962.01590090009004

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To the Editor:—  The interesting case of "Chronic Arsenical Intoxication" which was shown by Dr. Allen L. Lorincz and Dr. Maria Medenica in the Chicago Dermatological Society, Oct. 8, 1961 (published in Arch. Derm. 85:555-57 [April] 1962) showed localized hyperkeratotic lesions on the palms and feet. The patient had received arsenic injections for syphilis some years before.In the discussion, Dr. John Haserick and Dr. Theodore Cornbleet stated that they had never seen hyperkeratosis after arsphenamine (Salvarsan) treatment for syphilis.In 1921 when I was at Jadassohn's clinic I published a paper: "Beitrag zur Klinik der Salvarsanexantheme" Ther. Halbmonatshefte 35:370-74, 1921) in which I described some cases of localized palmar- and plantar-hyperkeratosis after Salvarsan.

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