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September 1962

Angiokeratoma Corporis Diffusum

Author Affiliations


Arch Dermatol. 1962;86(3):328-331. doi:10.1001/archderm.1962.01590090070016

A rare cutaneous disorder termed angiokeratoma corporis diffusum, first described in 1898 by Fabry, has appeared with increasing frequency. Until all facets of this condition have been explored, each new case should be investigated and reported. One previous case has been reported from Montana,1 but no hereditary relationship to this patient has been established.

Report of Case 

Patient's History.—  A 16-year-old white boy was first seen at the Great Falls Clinic on Aug. 5, 1960. His mother first noted lesions of the right leg, extending to the right heel, at the age of 5. An attempt was made to remove them with solidified carbon dioxide (dry ice), but keloid scarring resulted. Biopsy was made of this area in 1956 but was called "hemangioma." A review of this section August, 1960, by Dr. David Kersting2 reports "moderate hyperkeratosis, follicular plugging, subepithelial-lined, blood-filled, vascular spaces and small thromboses with proliferation in