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Article
October 1962

Progressive Pigmentary Disorder in Japanese Child

Arch Dermatol. 1962;86(4):412-418. doi:10.1001/archderm.1962.01590100026008
Abstract

A peculiar progressive symmetrical pigmentary dermatosis was observed. About 3 months after birth the patient developed a diffuse, black, India ink-like pigmentation on the dorsum of all fingers and toes in the pattern of acromelanosis or acropigmentation. There was also some pigmentation in the groins and on the thighs. Since then, the pigmentation spread quickly, over a period of 4 years, and typical tonic-clonic epileptic seizures were observed. The pigmentation was progressive not only in extent but also in intensity of the color. Histologic examination revealed a remarkably increased number of melanocytes at the epidermal-dermal junction. No typical nevus cells or nevus cell nests were found.

The case is considered an epidermal melanocytosis of nevoid character. The designation acromelanosis progressiva is proposed.

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