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January 1963

Triamcinolone and Hydrocortisone in Topical Therapy

Author Affiliations


USAF Hospital Andrews and Georgetown University School of Medicine.

Arch Dermatol. 1963;87(1):35-36. doi:10.1001/archderm.1963.01590130041009

Blank1 recently reported on the relative effectiveness of a lotion containing 0.01% triamcinolone acetonide compared to 1% hydrocortisone in 30 patients with atopic or seborrheic dermatitis. He and his co-workers found that in 28 of 30 patients the 0.01% triamcinolone was as effective or more effective than the 1% hydrocortisone, that is, in 10 of 30 the 0.01% triamcinolone was superior; in 18 of 30 the lotions were equally effective. Consequently, we sought further information on the subject.

Method and Materials

This study comprised 40 outpatients with various dermatoses: atopic dermatitis, 28; contact dermatitis, 5; lichen simplex chronicus, 2; numular eczema, 2; autoeczematization, 1; erythema multiforme, 1; and pityriasis rosea, 1. Each patient had bilateral symmetrical lesions so that a paired symmetrical comparison of the 2 creams could be done. The side of application of a particular cream was varied with successive patients so that no right or left

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