A pectin, gelatin, sodium carboxymethyl-cellulose, and plasticized hydrocarbon gel base (Orabase) may be used as a vehicle to test for contact allergy within the oral cavity. The suspected chemical is incorporated in the vehicle and applied to the oral mucosa.
Positive reactions are read in 24 hours. Six of 8 patients with proven skin allergy were also positive when tested in the oral cavity using this method.
ROSENBERG EW, FISCHER RW. Improved Method for Intraoral Patch Testing. Arch Dermatol. 1963;87(1):115–117. doi:10.1001/archderm.1963.01590130121019
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