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March 1963

Alopecia Totalis: Treatment with Fluocinolone Acetonide

Author Affiliations


Department of Dermatology, U.S. Naval Hospital.

Arch Dermatol. 1963;87(3):384-386. doi:10.1001/archderm.1963.01590150100019

Regrowth of hair in patients with alopecia areata and alopecia totalis has been demonstrated following intralesional injection or systemic administration with corticosteroid drugs.1-4 Intralesional injection is painful and may be followed by atrophy, and systemic administration is often accompanied by the undesirable effects of these drugs. The successful treatment of psoriasis and other dermatoses by maceration with fluocinolone acetonide cream under thin plastic films5 caused us to consider the use of this technique for the treatment of alopecia. The following case illustrates the regrowth of hair in a patient with alopecia totalis treated by this technique.

Report of Case  The patient, a 34-year-old housewife, was referred to us in April, 1962, because of alopecia of many years' duration. She had first noticed loss of hair behind her left ear in July, 1956. She became pregnant and in the second month of gestation the alopecia spread to involve her

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