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June 1963

Effect of Local Corticosteroids on Psoriasis: A Histopathologic Study

Author Affiliations


From the Section of Dermatology, Veterans Administration Hospital, and the University of Southern California Medical School (Dr. Reed and Dr. Becker).

Arch Dermatol. 1963;87(6):701-705. doi:10.1001/archderm.1963.01590180029006

Biopsy sections of psoriatic plaques that had been treated with intralesional triamcinolone acetonide or topical fluocinolone acetonide and occlusive dressings were examined for histopathological changes.

The findings were discussed, and a site of action of the steroids is proposed. The possible complications of local steroid therapy have been enumerated.