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June 1963

Steroid Therapy in Alopecia Universalis: A Case Report and Review of the Literature

Author Affiliations


Northern State Hospital, Sedro-Woolley, Wash and University of Washington School of Medicine, Seattle 5, Wash.

Arch Dermatol. 1963;87(6):706-709. doi:10.1001/archderm.1963.01590180034007

The literature concerning the etiology and treatment of alopecia is reviewed. A case is presented of alopecia universalis of 54 years' duration. The only significant systemic abnormality found on a thorough pretreatment evaluation of the patient was evidence of mildly decreased adrenal function. Skin biopsies before treament revealed no pathology except lack of a hair shaft. A rapid hair regrowth occurred after the institution of prednisolone therapy; the hair did not persist after the drug was withdrawn. The daily dosage of steroid necessary to produce hair regrowth was found to be less than the average daily endogenous steroid secretion of normals.