Although much dermatologic knowledge derives from careful qualitative observation, there is increasing need for quantitative data to support our qualitative impressions.
The principle of a syringe driven by a screw or a micrometer was known to both Kelvin and Lister, the former measuring large volumes of gas in the constant pressure gas thermometer, and the latter measuring small quantities of fluid in bacteriologic research. The instrument* we use was described by Trevan in 1925.1 Since that time the instrument has been used mainly by the chemist. We know of one reference of its use in animal biology.2
The instrument consists essentially of three parts: (1) An all-glass syringe standardized by the manufacturer. The syringe takes a standard 27- or 30-gauge Luer-type needle. Both are readily sterilized ; (2) a metal holder which connects the syringe to the micrometer; and (3) a micrometer which rotates forward the piston of the
MAIBACH HI, KLIGMAN AM. The Micrometer Syringe for Quantitative Skin Testing. Arch Dermatol. 1963;87(6):743–744. doi:10.1001/archderm.1963.01590180071015
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