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June 1963


Author Affiliations

Chief, Dermatological Service Hospital General San Felipe Tegucigalpa, Honduras, C. A

Arch Dermatol. 1963;87(6):745-746. doi:10.1001/archderm.1963.01590180073017

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To the Editor:—In Archives of Dermatology, November, 1962, page 634, there is an interesting paper by Dr. Robert E. Lyons, from San Antonio, Texas. Dr. Lyons' case of sporotrichosis was treated with 1 gm of griseofulvin daily, during eight weeks, and additional treatment with x-rays was given at the same time. The patient was cured and the lesions healed completely in eight weeks.

In Honduras, Central America, sporotrichosis is very common, especially the lymphangitic type, localized to arms and legs. In view of the results obtained by Dr. Lyons in his case, I decide to use the drug in my next patient.

The patient was a young man, with typical sporotrichosis of the left arm with three months of evolution. Culture on Sabouraud's agar was positive for Sporotrichum Schenkii. Griseofulvin was administered in a dose of 1 gm daily in two divided doses for six weeks. No x-rays or other treatment was used. At the end of six weeks the lesions showed no improvement, and we were able to culture the fungus again from the active lesions.

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