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June 1963


Arch Dermatol. 1963;87(6):749-752. doi:10.1001/archderm.1963.01590180077019

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Benign Chronic Familial Pemphigus. Presented by Dr. Lee Carrick.

A white man, age 56, was well until he was 28 years old at which time he developed blisters and crusted patches along the sides of his neck. His course has been chronic and characterized by exacerbations and remissions.

The patient's father had a "rash" on his neck, arms, and shoulders for 20 years prior to his death. A sister, age 41, has had "dried up patches around her neck" for the past 12 years. Two male siblings aged 54 and 44, are living and well and present no dermatological complaints.

The physical examination showed a normal-appearing healthy man with a 2 × 4 cm moist, verrucous, oval-shaped plaque in the left axilla and multiple, discrete, infiltrated, crusted patches (the average 1 cm in diameter) distributed over the preclavicular and manubrial surfaces. In addition, scaling was seen over the scalp, eyebrows,

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