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June 1963

Investigations Into Dyshidrosiform Eruptions

Arch Dermatol. 1963;87(6):791. doi:10.1001/archderm.1963.01590180119029

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The monograph is a serious attempt to elucidate the nature of the conditon(s) named in the title. Reports by other investigators, as well as investigations undertaken by the author, are utilized in this effort. The first part of the treatise deals with the question whether or not the sweat apparatus plays any role in bringing about the eruptions. This part includes (a) histopathological findings and considerations, (b) comparative pH investigations of vesicular contents and "sweat" on the skin surface, and (c) a description of seasonal fluctuations in the occurrence of the eruption. Some observations of the influence of pilocarpine, acetylcholine, and of exposure to heat or to sunlight are reported as well. The second part is devoted to the question of an interrelationship between dermatophytids and dyshidrosiform conditions. There are, moreover, comments on the concept of ``allergids'' in a more general sense, as well as on the importance of unspecific

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