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July 1963


Arch Dermatol. 1963;88(1):91-96. doi:10.1001/archderm.1963.01590190097018

Nevus Syringocystadenomatosus Papilliferus. Presented by Drs. Silas Wallk, Harold H. Rodin and (by invitation) J. Bettenhausen.

Four years ago this ten-year-old Negro male developed a rough-surfaced, slightly hyperpigmented patch on his scalp. This patch is mildly pruritic. The lesion is not enlarging at the present time.

A biopsy is submitted for examination. This biopsy revealed cystic papillary invaginations extending downward from the epidermis and lined by two layers of cells. The stroma between the papillary projections was infiltrated by chronic inflammatory cells and showed also dilated engorged vessels.


Dr. David Kersting, Milwaukee: This lesion has some soft verrucous papules, but also a crusted surface coagulum (biopsy site?), and some hyperkeratosis which is difficult to interpret. The clinical differential diagnosis would include basal cell epithelioma, irritated verruca vulgaris, the "warty dyskeratoma" of Szymanski, the syringoadenoma papilliferum, and nevus sebaceus. The section shows a proliferation of apocrine-like epithelium lining sinuses embedded