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August 1963

Alopecia Universalis, Onychodystrophy, and Total Vitiligo

Arch Dermatol. 1963;88(2):195-201. doi:10.1001/archderm.1963.01590200083017

Two patients with the syndrome of alopecia universalis, onychodystrophy, and apparent total vitiligo are reported. Extensive investigations including endocrinologic evaluation and viral cultures failed to reveal a systemic abnormality or evidence of an etiologic agent. These three entities are discussed and their etiological interrelationships considered.