[Skip to Navigation]
August 1963


Arch Dermatol. 1963;88(2):235-237. doi:10.1001/archderm.1963.01590200123032

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.


Peutz-Jeghers' Syndrome. Presented by Dr. Willard M. Meininger.

A 71-year-old woman had "brown spots" on her lips since 1960. She is unaware of any similar condition in the family. Her father died of a carcinoma of the colon at age 64, but she does not believe he had hyperpigmentation of his lips.

During October of 1960 she complained of fatigue and bloody stools. Gastrointestinal series and barium enema revealed the presence of a hiatus hernia, a duodenal diverticulum, and polyp in both the sigmoid and transverse colon. A previous barium enema in January, 1959, had failed to reveal any abnormalities. Both polyps were removed; the lesion in the sigmoid colon proved to be an adenocarcinoma, and the transverse colon polyp showed premalignant hyperplasia.


Dr. Edward J. Ringrose: I saw a woman with similar spots on her lips. She was referred by a general practitioner. She had been on corticosteroids

First Page Preview View Large
First page PDF preview
First page PDF preview