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September 1963

Trauma in Experimental Superficial Cutaneous Infections

Author Affiliations


Department of Dermatology of the Harvard Medical School at the Massachusetts General Hospital.

Arch Dermatol. 1963;88(3):276-279. doi:10.1001/archderm.1963.01590210034005

Experimental, superficial, streptococcal cutaneous infections were produced by repeated stripping of the skin of hairless mice before inoculation with a broth containing streptococci.

Fifteen or more strippings were necessary to produce a crusted lesion.

Pathological examination of biopsies taken from the denuded skin of mice inoculated with live streptococci immediately after stripping, showed that the bacteria delayed the process of reepithelialization in the stripped wound.

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