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October 1963

The Dermal Elastoses

Author Affiliations


From the Division of Dermatology, Department of Medicine and the Center for the Study of Aging, Duke University Medical Center. Presented before the 83rd meeting of the American Dermatological Association, The Homestead, Hot Springs, Va, April 16, 1963.

Arch Dermatol. 1963;88(4):382-392. doi:10.1001/archderm.1963.01590220014002

The evidence that elastin is fundamentally different from collagen has been reviewed.

With this background, a new classification based on etiology and distribution has been introduced for the dermal elastoses (those diseases associated with increased elastic tissue staining).

Using the criteria which differentiate elastin from collagen, each of the elastoses has been evaluated. The elastotic fibers seen histologically in actinic elastosis and pseudoxanthoma elasticum are more characteristic of elastin than collagen.

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