A report is presented on a family of 25 members through five generations; among these ten had keratosis punctata palmaris et plantaris.
The defect seems to be inherited as a regular dominant trait.
The condition may not appear until late in life.
The severity of the disturbance varied considerably, and if awareness of the condition and careful examination is not followed, the defect might easily pass unnoticed.
Explanations are offered which might reconcile the reports of nonfamilial occurrence and recessive inheritance with the concept of dominant inheritance.