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December 1963

Sebaceous Gland Function Before and After Bilateral Orchiectomy

Author Affiliations


From the Department of Dermatology and Evans Memorial Department of Clinical Research, Massachusetts Memorial Hospitals, and Department of Dermatology, Boston University School of Medicine, Boston University Medical Center.

Arch Dermatol. 1963;88(6):729-731. doi:10.1001/archderm.1963.01590240053009

Sebum production has been studied in a group of eight elderly patients before and for one year after orchiectomy. A significant decrease in sebum production was observed in the six patients who had a bilateral orchiectomy performed for adenocarcinoma of the prostate gland. The decrease was evident in one month. During a one-year follow-up, these patients demonstrated a slight to moderate increase in sebum production from the initial low values observed in the early months after castration.

The other two patients had only a unilateral orchiectomy. In one patient, the ablation of a functional testis caused a reduction in sebum output, but in the other patient no significant change occurred following the removal of an atrophic testis.

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