[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address 34.204.200.74. Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Article
February 1964

Manifestations of Familial Autonomic Dysautonomia: Report of a Case, With an Analysis of 125 Cases in the Literature

Author Affiliations

NEW YORK

Resident, The Department of Dermatology, The Mount Sinai Hospital.

Arch Dermatol. 1964;89(2):190-195. doi:10.1001/archderm.1964.01590260028004
Abstract

A typical case of familial autonomic dysautonomia is described. A review of the 124 previously reported cases has been made with an analysis of the pertinent findings. The essential features are defective lacrimation, blotching of the skin, excessive sweating, and excessive drooling, which are observed during infancy. Less constant findings are emotional instability, blood pressure lability, pain indifference, and faulty speech. Approximately one third of the cases have a definite familial history. To date, dysautonomia has been reported only in Caucasians. The syndrome is most likely genetically determined, involving enzymatic defects in the metabolism and function of the catecholamines.

×