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March 1964

X-Ray Microscopy and Microangiography: Their Potential Value

Author Affiliations


From the Department of Anatomy, Dalhousie University, Halifax (Dr. Saunders) and the Oregon Regional Primate Research Center, Beaverton (Dr. Montagna).

Arch Dermatol. 1964;89(3):451-454. doi:10.1001/archderm.1964.01590270137031

Introduction  The methods for studying cutaneous blood vessels are to inject them with opaque substances, to stain them selectively, or to observe them directly from the living surface of the skin. To study the vessels which have been injected or stained, one has to section the skin, or clear it, and neither method is completely satisfactory. Direct observations allow a very limited view of the vessels.The technique of x-ray projection, perfected by Saunders,1 offers unparalleled opportunities for studying the volume and patterns of vessels in whole skin, without the necessity of sectioning it. The technique offers a new and promising approach to the study of normal, pathologic, and experimental skin conditions that not many know about. The purpose of this publication is to demonstrate the potentials of x-ray microscopy and microangiography with a series of photographs.

Material and Methods  Human skin was prepared for microangiography by injecting

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