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March 1964


Arch Dermatol. 1964;89(3):482-483. doi:10.1001/archderm.1964.01590270168041

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Darier's Disease (Dyskeratosis Follicularis) in Father and Son. Presented by Dr. Herbert H. Johnson, Jr. 

History.—  The patient, a 48-year-old man, first noted light brown papules on the neck and trunk at age ten. A diagnosis of Darier's disease was made by Dr. LaRocco when the patient was 12 years old and confirmed by biopsy in 1943 while he was in the army.His past medical history is not significant; his family history reveals a son (and possibly a nephew) with Darier's disease.Examination revealed a well-developed and wellnourished white male with numerous light brown, slightly verrucous papules, 2 to 6 mm in size, scattered over the body generally, but most numerous on lateral neck, upper back, and lateral thorax. On the right pretibial skin there is a hypertrophic confluent lesion.The son of the patient, age 13, first noted a recurrent rash on the anterior neck at age six,

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