Study of a patient with recurrent erythema annulare centrifugum of eight years' duration revealed it to be due to hypersensitivity to Penicillium mold of blue cheese. Oral test administration of blue cheese produced a rapid flare and extension of the lesions with a concomitant specific degranulation and decrease in the circulating basophil leukocytes. Complete avoidance of blue cheese has resulted in clinical clearing.
SHELLEY WB. Erythema Annulare Centrifugum: A Case Due to Hypersensitivity to Blue Cheese Penicillium. Arch Dermatol. 1964;90(1):54–58. doi:10.1001/archderm.1964.01600010060012
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